Software-defined radios (SDRs) and cognitive radios have already transformed the telecommunications. As hardware that can support powerful deep network implementations in small form-factors  advances, sophisticated AI-enabled communications and networking protocols can be expected to be ubiquitous. In many wireless network applications, cognitive interference mitigation and avoidance, for example, offer a solution for dynamic spectrum management and spectrum coexistence. In adversarial scenarios, AI-enabled cognitive jamming/anti-jamming and cognitive spoofing/anti-spoofing protocols are essential for maintaining reliable network connectivity.